Ultra-Acute Stroke: The Rapid Intervention With Glyceryl Trinitrate in Hypertensive Feasibility of an Ambulance-Based Stroke Trial, and Safety of Glyceryl Trinitrate in
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چکیده
Sandeep Ankolekar, Michael Fuller, Ian Cross, Cheryl Renton, Patrick Cox, Nikola Sprigg, A. Stroke Trial (RIGHT, ISRCTN66434824) Ultra-Acute Stroke: The Rapid Intervention With Glyceryl Trinitrate in Hypertensive Feasibility of an Ambulance-Based Stroke Trial, and Safety of Glyceryl Trinitrate in Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2013 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke doi: 10.1161/STROKEAHA.113.001301 2013;44:3120-3128; originally published online September 3, 2013; Stroke. http://stroke.ahajournals.org/content/44/11/3120 World Wide Web at: The online version of this article, along with updated information and services, is located on the http://stroke.ahajournals.org/content/suppl/2013/09/03/STROKEAHA.113.001301.DC1.html Data Supplement (unedited) at:
منابع مشابه
Feasibility of an ambulance-based stroke trial, and safety of glyceryl trinitrate in ultra-acute stroke: the rapid intervention with glyceryl trinitrate in Hypertensive Stroke Trial (RIGHT, ISRCTN66434824).
BACKGROUND AND PURPOSE The practicalities of doing ambulance-based trials where paramedics perform all aspects of a clinical trial involving patients with ultra-acute stroke have not been assessed. METHODS We performed a randomized controlled trial with screening, consent, randomization, and treatment performed by paramedics prior to hospitalization. Patients with probable ultra-acute stroke ...
متن کاملViews of paramedics on their role in an out-of-hospital ambulance-based trial in ultra-acute stroke: qualitative data from the Rapid Intervention With Glyceryl Trinitrate in Hypertensive Stroke Trial (RIGHT).
STUDY OBJECTIVE Optimal practices for recruiting, consenting, and randomizing patients, and delivering treatment in out-of-hospital ultra-acute stroke trials, remain unclear. We aim to identify key barriers and facilitators relevant to the design and conduct of ambulance-based stroke trials and to formulate preliminary recommendations for the design of future trials. METHODS Using semistructu...
متن کاملDetermining the Feasibility of Ambulance-Based Randomised Controlled Trials in Patients with Ultra-Acute Stroke: Study Protocol for the “Rapid Intervention with GTN in Hypertensive Stroke Trial” (RIGHT, ISRCTN66434824)
Background. Time from acute stroke to enrolment in clinical trials needs to be reduced to improve the chances of finding effective treatments. No completed randomised controlled trials of ambulance-based treatment for acute stroke have been reported in the UK, and the practicalities of recruiting, consenting, and treating patients are unknown. Methods. RIGHT is an ambulance based, single-blind,...
متن کاملStatistical analysis plan for the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial
High blood pressure is common during the acute phase of stroke and is associated with a poor outcome. However, the management of high blood pressure remains unclear. The 'Efficacy of Nitric Oxide in Stroke' trial tested whether transdermal glyceryl trinitrate, a nitric oxide donor that lowers blood pressure, is safe and effective in improving outcome after acute stroke. Efficacy of Nitric Oxide...
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Background: Tennis elbow (TE), as a lateral epicondylitis (LE), is a chronic inflammatory and degenerative tendon disease that causes pain in the outer part of the elbow. This study aimed to evaluate the efficacy of topical Trinitrate Glyceryl (GTN) in the treatment of patients with TE. Materials and methods: In this double-blind clinical trial, 90 patients with TE, referred to Orthopedic and R...
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تاریخ انتشار 2014